Acantholysis

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Acantholysis

Definition
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Dissolution of the epithelial cell assembly with single cell formation and intraepidermal cleavage and blistering due to immunologically or genetically induced alteration of the desmosomes, e.g. in pemphigus vulgaris, dyskeratosis follicularis, pemphigus chronicus benignus familiaris, transitory acantholytic dermatosis (Grover), due to cell death of the epithelial cells, e.g. in viral vesicles (herpes simplex), bacterial infections ( impetigo) or in the case of malignant degeneration (e.g. spinocellular carcinoma).

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Last updated on: 29.10.2020