Amoxicillin

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

amoxycillin

Definition
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Penicillin belonging to the group of aminobenzylpenicillins.

Half-life
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0,5–1 h

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Dosage and method of use
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  • 2-4 g/day p.o. or i.v. in 3-4 ED.
  • Children from 3 months: 250-500 mg/day.
  • Children from 6 months: 300-600 mg/day.
  • Children from 1 year: 350-750 mg/day.
  • Children from 3 years: 500-1000 mg/day.
  • Children from 7,5 years: 750-1500 mg/day.
  • Children from 12 years: 1-2 g/day.

Undesirable effects
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Gastrointestinal symptoms such as diarrhoea, exanthema (1-2% of cases; more common in patients with infectious mononucleosis and other viral diseases, lymphatic leukemia); fever, transaminase increase (rare), interstitial nephritis (rare); hepatitis/cholestasis (rare).

Preparations
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Amoxicillin, Amoxy-Tablines, Amoxypes, Infectomox

Literature
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  1. Arnez M (2007) Antibiotic treatment of children with erythema migrans. Clin Infect Dis 44: 1133-1134
  2. Larrey D et al (1992) Hepatitis associated with amoxycillin-clavulanic acid combination report of 15 cases. Good 33: 368-371

Outgoing links (2)

Aminobenzylpenicillins; Penicillin;

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Last updated on: 29.10.2020