Cutis aurantiasis E67.1

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Carotene jaundice; Carotenosis; Carotenosis and hypercarotenemia; Carotinosis; Hypercarotenemia; Xanthochromia; Xanthosis

History
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Baelz 1896

Definition
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Nutritive or metabolically induced, harmless yellowing of the skin.

Etiopathogenesis
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Excessive consumption of carrots, oranges or tomatoes or by drinking carotene-containing fruit juices; also as a result of elevated serum lipoid levels in diabetes mellitus, nephrosis syndrome, hypothyroidism or primary hypercholesterolemic xanthomatosis

Harmless in small children due to the special dietary requirements (carrot icterus). If plasma carotenoid levels of 4.0mg/l are exceeded over a longer period of time, carotene accumulates in the keratin of the skin.

This leads to a yellowing of hyperkeratotic areas such as the palms of the hands, soles of the feet and the face.

Localization
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Especially Palmae (palm lines), Plantae, face (conjunctivae free!), armpits.

Clinical features
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Yellowing of the skin and nails with reinforcement on palms of hands and soles of feet. In particular, the palm lines are more intensely coloured.

Histology
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Yellowing of the entire epidermis, especially the horny layer.

Differential diagnosis
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Icterus: Bilirubin elevation; yellowing of the sclerae; liver diseases (e.g.hepatitis, cirrhosis of the liver)!

Chrysiasis: brown colouring of the skin, accentuated by light! Medical history.

Argyrie: Dirty brown colouring of the skin, light accentuated! Medication history (roller cures).

Xanthoderma: yellowing of the skin as a side effect of a mepacrin therapy (antiepileptic) or a therapy with Qinacrin or Sorafenib.

dyschromia caused by drugs such as: minocycline, amiodarone, imipramine, clofazimine, hydroxychloroquine

Exogenous dyschromia: discoloration of the contact zones.

Therapy
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Change of diet, clarification and treatment of the underlying disease.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020