Exanthema, acneiformes R21.x

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

acne medicamentosa

Definition
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Predominantly drug-induced skin symptoms with acne-like efflorescences, but without comedones. S.a. Acne medicamentosa.

Etiopathogenesis
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Possible triggers are above all: glucocorticoids ( steroid acne), also ACTH, diphenylhydantoin, quinine, isoniazid. Furthermore: halogen-containing drugs like iodine compounds, bromine compounds. Furthermore: lithium, phenobarbiturates, disulfiram, thyrostatic drugs (thiourea, thiouracil). Furthermore: vitaminB1, B6, B12, tyrosine kinase inhibitors like cetuximab (belongs together with gifitinib and erlotinib to a group of cancer therapeutics whose common feature is the blockade of the epidermal growth factor receptor[ EGF-receptor]; acne-like skin changes occur in > 80% of cases, about 2-6 weeks after the start of therapy).

Localization
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Especially in the seborrhoeic zones and the upper arms.

Therapy
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Stop the medication. S.a.u. Acne medicamentosa.

Literature
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  1. Braun-Falco M et al (2006) Follicular drug reaction to cetuximab. dermatologist 57: 701-704

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020