Vardenafil

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Indication
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Impotentia coeundi (erectile dysfunction).

Dosage and method of use
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If necessary: Take 10-20 mg once a day 20-60 minutes before sexual intercourse. Initial: 5-10 mg p.o.

Remember!

Do not exceed the maximum daily dose of 5 mg when using erythromycin at the same time!

Remember! The effect lasts up to 4-6 hours after ingestion!

Undesirable effects
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Often headaches, dyspepsia, nausea, dizziness, rhinitis.

Notice! Photosensitivity.

Interactions
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CYP3A4, CYP3A5 or CYP2C inhibitors: reduction of vardenafil clearance and enhancement of the antihypertensive effect of calcium antagonists (e.g. nifedipine).

Contraindication
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Not for women and patients < 18 LJ, severe cardiovascular disease, liver or kidney failure. Comedication with CYP-3A4 inhibitors such as cimetidine, erythromycin, ketoconazole, ritonavir. Antihypertensive therapy with nitrates, NO-donors (e.g. amyl nitrite, molsidomine) because of potentiation of the blood pressure lowering effect.

Preparations
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Levitra

Note(s)
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Remember! Ability to participate in road traffic and to operate machines may be affected!

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Last updated on: 29.10.2020