Raynaud's disease I73.0

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Primary Raynaud's syndrome; Raynaud's disease

History
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Raynaud, 1862

Definition
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Primary Raynaudian phenomenon. Negative variant: digitus mortuus.

Remark: Basically the clinical symptoms of Raynaud's disease (synonymous with "primary Raynaud's syndrome") do not differ from those of Raynaud's syndrome and are treated and updated under this comprehensibility.

Etiopathogenesis
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Idiopathic, triggers: Cooling stimulus, especially temperatures around 12-16 °C, endocrine factors: dysfunction of the thyroid and pituitary gland, frequent familial occurrence.

Manifestation
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Occurs in early adulthood, especially in women.

Localization
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Especially the index and middle fingers are affected.

Clinical features
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Symmetrical seizures in three stages, accompanied by paresthesia, numbness, tingling and burning sensation and pain at the transition from cyanosis to redness.
  • Phase 1: Paleness of one or more fingers.
  • Stage 2: Cyanosis.
  • Stage 3: Redness due to reactive hyperemia.
The individual phases may vary in severity. Duration of the attack: about 10 minutes in mild cases and initial stages, 30 to 120 minutes in severe cases or later stages.
  • In the chronic stage dystrophic skin of the affected fingers, nail dystrophy, wound healing disorders. The formation of symmetrical necroses limited to the fingertips, ranging from symmetrical to pinhead-sized necroses, is possible.

Diagnosis
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Clinic, nail fold capillaroscopy, pulse oscillography with cold provocation.

Differential diagnosis
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Therapy
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According to the Raynaudian phenomenon.

Progression/forecast
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Recurrent course. Development of sclerodactyly is possible.

Literature
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  1. Raynaud AGM (1862) De l'asphyxie locale et de la gangrène symétrique des extrémités. Doctoral thesis, Rignoux, Paris
  2. Raynaud M (1888) On asphyxia and symmetrical gangrene of the extremities 1862 and new researches on the nature and treatment of local asphyxia of the extremities 1874 Translated by T. Barlow In: Selected Monographs, New Sydenham Society, London, S. 1-199

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020